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Development of a Composite Diagnostic Biomarker for Amyotrophic Lateral Sclerosis: Experimental Approach and Progress to Date
Lead Author: Jamie Timmons, MD
Published: Northeast ALS Consortium Annual Meeting (NEALS)
Date: October 4 - 6, 2023
Novel Neuroprotective Strategies in Human Neuron Models of ALS/FTD: Evaluating Antisense Oligonucleotide Therapies, including AMX0114
Lead Author: Sami Barmada, MD, PhD
Published: Northeast ALS Consortium Annual Meeting (NEALS)
Date: October 4 - 6, 2023
Ongoing and Planned Studies to Further Elucidate the Efficacy, Safety, and Pharmacokinetics of Sodium Phenylbutyrate and Taurursodiol in Amyotrophic Lateral Sclerosis
Lead Author: Jamie Timmons, MD
Published: Northeast ALS Consortium Annual Meeting (NEALS)
Date: October 4 - 6, 2023
Preliminary Experience With Sodium Phenylbutyrate and Taurursodiol in a United States Expanded Access Program
Lead Author: Machelle Manuel, PhD
Published: Northeast ALS Consortium Annual Meeting (NEALS)
Date: October 4 - 6, 2023
Real-World Experience and Strategies to Enhance the Palatability of the Combination Sodium Phenylbutyrate and Taurursodiol for the Treatment of Amyotrophic Lateral Sclerosis
Lead Author: Jamie Timmons, MD
Published: Northeast ALS Consortium Annual Meeting (NEALS)
Date: October 4 - 6, 2023
Update on AMX0114: An Antisense Oligonucleotide Targeting Calpain-2, a Critical Effector of Axonal Degeneration
Lead Author: Jamie Timmons, MD
Published: Northeast ALS Consortium Annual Meeting (NEALS)
Date: October 4 - 6, 2023
Characterization of the Enrolled Population in the Phase 3 PHOENIX Trial in Amyotrophic Lateral Sclerosis: Preliminary Results
Lead Author: Leonard van den Berg (Presenter)
Published: European Network to Cure ALS (ENCALS)
Date: July 12 - 14, 2023
Efficacy of Sodium Phenylbutyrate and Ursodoxicoltaurine Combination in Transgenic Mice Displaying Progressive Motor Neuron Degeneration Phenotype
Lead Author: Jamie Timmons (Presenter)
Published: European Network to Cure ALS (ENCALS)
Date: July 12 - 14, 2023
Effect of an Oral, Fixed-Dose Combination of Sodium Phenylbutyrate and Taurursodiol on Long-Term Tracheostomy/Ventilation-Free Survival and Hospitalization in Amyotrophic Lateral Sclerosis: Final Results From CENTAUR
Lead Author: Janelle Schafer (Presenter)
Published: International Society for Pharmacoeconomics and Outcomes Research (ISPOR)
Date: May 6 - 10, 2023
Development and Preclinical Assessment of AMX0114: an Antisense Oligonucleotide Targeting Calpain-2, a Critical Effector of Axonal Degeneration
Lead Author: Joshua Cohen, Co-CEO and Co-Founder, Amylyx Pharmaceuticals
Published: Muscular Dystrophy Association (MDA)
Date: March 19 - 22, 2023